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Introduction
The purpose of this study is to determine tumor gene expression profiles (GEP) from dogs with lymphoma (LSA) prior to treatment with chemotherapy and at 1st relapse. Specifically, we plan to identify unique GEP that may define specific subtypes of LSA and that may impact diagnosis, treatment, response to chemotherapy, and development of new treatments.
Eligibility Requirements
ü Any K9 breed, age, sex in otherwise good health
ü Cytologically or histologically confirmed multicentric LSA
ü No previous chemotherapy or steroids
ü Staging diagnostics
ü Willingness to treat with the modified Wisconsin Protocol
o 16 treatments over a 6-month period
ü Pre-treatment blood sample and biopsy
ü Blood sample and biopsy at time of relapse
ü Owner consent
Client Incentive
ü The costs of the biopsy (including sedation) will be covered by the study
ü Histology and immunophenotyping will be performed at no cost
ü $500 will be reimbursed to the client at the time of relapse and subsequent biopsy
Contact Information
Please call The Oncology Department at Florida Veterinary Specialists & Cancer Treatment Center at (813) 933-8944 if you have further questions regarding the study or enrollment criteria.
This study is being sponsored by the Morris Animal Foundation and is being conducted in collaboration with The Ohio State University College of Veterinary Medicine, The Ohio State University Comprehensive Cancer Center and other collaborating veterinary oncologists.
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